The artist has given the complete sum of his £25,000 award prize money to the trust for venues, which functions to save the Britain's grassroots concert spaces.
He was given the prize on 16 October as his new release his work was named the top album of the last 12 months.
He has opted to hand the money over to the trust, in recognition of the essential function local spots had in his initial steps.
"As an artist wouldn't be doing my current career if it wasn't for all the performances I performed around the area, and further afield, when I was just getting going," said Sam Fender. "These spaces are legendary, but they are in difficulty."
From early 2023 onward, over 150 of these spaces have permanently closed – about 16% of the total UK scene.
Recently, major artists like Pulp, the group Coldplay, Katy Perry and Ed Sheeran have all aided the MVT in its initiatives to help venues survive, by including a modest fee to their ticket prices, which goes to help local stages.
Fender also joined in, generating in excess of £100,000 on his recent tour to support numerous grassroots venues across England, Scotland, and Wales.
The money assisted locations that were facing potential shutdown due to challenges caused by floods, blazes and family tragedies, as well as regulatory hurdles, legal disputes and sound issues.
Additional spaces obtained funding support in upgrading amenities and gear that helped musicians and fans.
"The idea that money from concerts in large arenas supports the independent spots, where it all starts for performers like me, is just sensible," the star has commented.
The musician is not the first artist to give his Mercury Prize funds to worthy causes.
Back when the band received the prize in 1996 for their album Different Class, vocalist the singer announced that the act would contribute their prize money to the non-profit War Child.
During 2002, rapper and singer Ms Dynamite divided her prize across multiple organizations, including the children's charity and a Sickle Cell organization.
"I also contributed a £1,000 to the center, to their gymnastics program, because I practiced gymnastics when I was growing up and they lacked updated gear," she told outlets.
In recent years, the band contributed their winnings to the community center that nurtured their act, in addition to other grassroots music organisations.
And 1994 winners the group gave their prize to a charity for MS after a friend was diagnosed the condition.
"The victory was sufficient," said singer Heather Small. "The money was the extra but we didn't require the cherry, because we had the main prize. So our success touched somebody else's life."
Last week, the MVT shared it had saved several small stages in the South East, by placing them under community ownership.
One venue in the city and the other in the city were bought under the public acquisition program, which is funded by Arts Council England and supporters who buy "ownership units" in the properties.
